Ginsenoside Re Attenuates Isoproterenol-Induced Myocardial Injury in Rats
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چکیده
منابع مشابه
Ginsenoside Rg2 attenuated myocardial injury induced by isoproterenol in rats
The present study was designed to investigate the effect of ginsenoside Rg2 on myocardial injury induced by isoproterenol in rats. Sprague-Dawley rats were subcutaneously injected with isoproterenol (20 mg/kg). Creatine kinase-MB (CK-MB) activity and troponin T level in serum, antioxidative parameters, and inflammatory cytokines in left ventricles were measured. Histopathological examination of...
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The purpose of the present study was to gain a better understanding of the relation between ventricular remodeling and heart failure by assessing the adaptation of the heart through time to graded myocardial injury in the presence of a patent coronary circulation. Left ventricular (LV) remodeling is a dynamic response of the heart to injury and a critical component in the development of heart f...
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Diabetes mellitus is associated with decreased NO bioavailability in the myocardium. Ginsenoside Rb1 has been shown to confer cardioprotection against ischemia reperfusion injury. The aim of this study was to investigate whether Ginsenoside Rb1 exerts cardioprotective effects during myocardial ischemia-reperfusion in diabetic rats and whether this effect is related to increase the production of...
متن کاملRegulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats.
OBJECTIVES This study was designed to investigate the cardioprotective effects of matrine on regulation of endothelial nitric oxide synthase (eNOS) and asymmetric dimethylarginine (ADMA) in isoproterenol-induced acute myocardial ischaemic rats. METHODS Male Sprague-Dawley rats were pretreated with matrine (200, 100 and 50 mg/kg) orally for 10 days. Acute myocardial injury was induced in rats ...
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CGEN-856S is a novel Mas agonist. Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury. We also sought to determine whether CGEN-856S activates the underlying mechanisms related to Mas receptor activation. Heart hypertrophy and fibrosis were induced by ISO (2 mg·kg(-1)·day(-1)) in Wistar rats. After a 7-day treat...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2018
ISSN: 1741-427X,1741-4288
DOI: 10.1155/2018/8637134